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HIV Symptoms And Info
By Anil Shaw

HIV Symptoms And Info

The major problem with relying on symptoms to detect or AIDS is that sometimes these conditions show no sign of their presence at all. You may feel and look great and still be positive. Now that is a scary fact. And the reality is, you may be passing on the disease to others without even realizing it.

Now to avoid the guilt of this and to take action on your own condition, if you have even the smallest suspicion that you are suffering from HIV, get a test done to confirm it. That is the only way you will ever know.

However, some people do exhibit various symptoms and it is important to note them as well. Perhaps you do not suspect that you have contracted at all and are not even thinking about that possibility. That is when being aware of the symptoms to look out for can come in handy.

Now, without further adieu, here are the major symptoms those with complain of:

-A fever that you cannot seem to get rid of
-Persistent diarrhea
-Headache
-Swollen glands in the neck, groin and/or armpits
-White spots on the tongue, throat or in the mouth
-Night sweats
-Dry cough
-Fatigue
-Blotches on the skin or under it. Can also appear in the mouth, nose or on the eyelids. They are usually purple, brown or red in color.

And some of the more serious symptoms include:

-Depression
-Pneumonia
-Weight loss
-Memory loss

As the virus takes over the white blood cells, the virus then causes AIDS.

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AIDS occurs when the immune system has been severely weakened by the virus and you either develop something called an opportunistic infection, or an infection that occurs because your immune system is so “down,” or your lymphocyte count is below 200.

Some symptoms associated with an opportunistic infection caused by the progression of the virus include:

-Severe chills
-Severe night sweats
-Persistent fever of over 100 F
-Blurred vision
-Rapid weight loss
-Shortness of breath
-Severe diarrhea
-Lesions in the mouth, on the tongue or in the throat that will not go away.

The development of cancer is also more likely in those with advanced disease.

The most common killer of those with advanced or AIDS is Pneumocystis carinii pneumonia or PCP—an opportunistic infection and type of pneumonia that develops exclusively in AIDS patients.

Contracting or AIDS used to be a death sentence. And while there is still no cure, treatments have improved vastly. The AIDS drug “cocktail” has helped many people live longer and happier lives than ever thought possible with the disease. Plus, new medical treatments are helpful prolong the period of time before turns into AIDS. These are all great developments and who knows what the future will bring?

 

 Key words: Health, health info, HIV, Treatment, Cure, Test,AIDS,Cancer,Kidney Problems


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Asserting "we are at an exceptional moment" in the hunt for an Alzheimer'sdiseasetreatment, National Institutes of Health director Dr. Francis Collins on Tuesday promised a raft of new research aimed at stopping and reversing the memory-robbing disorder by the year 2025. In unveiling a first-ever "national strategy" on Alzheimer's disease, Collins launched several new projects and clinical trials--including a whole-genome sequencing effort to identify genes that confer vulnerability to--or protection against-- Alzheimer's, and a trial to explore whether an inhaled form of insulin will slow progression of the disease.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f63d777/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=National+strategy+on+Alzheimer%27s+disease+aims+to+halt+it+by+2025&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-alzheimers-national-strategy-20120515%2C0%2C4694611.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=National+strategy+on+Alzheimer%27s+disease+aims+to+halt+it+by+2025&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-alzheimers-national-strategy-20120515%2C0%2C4694611.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204266514/u/49/f/622900/c/34253/s/1f63d777/a2.htm"><img src="http://da.feedsportal.com/r/134204266514/u/49/f/622900/c/34253/s/1f63d777/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204266514/u/49/f/622900/c/34253/s/1f63d777/a2t.img" border="0"/>
Parkinson's disease may be diagnosed by studying colon, reports say
Parkinson's disease is a disorder of the brain, but it may be possible to diagnose it at an early stage by examining the bowel, researchers said Tuesday. As new drugs to treatParkinson's are developed, they noted, earlier diagnosis should make it possible to intervene at an earlier stage when the disorder is more susceptible to drugs, thereby prolonging quality of life and lifespan.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f6306a0/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Parkinson%27s+disease+may+be+diagnosed+by+studying+colon%2C+reports+say&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-parkinsons-colon-20120515%2C0%2C4151878.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Parkinson%27s+disease+may+be+diagnosed+by+studying+colon%2C+reports+say&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-parkinsons-colon-20120515%2C0%2C4151878.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204535043/u/49/f/622900/c/34253/s/1f6306a0/a2.htm"><img src="http://da.feedsportal.com/r/134204535043/u/49/f/622900/c/34253/s/1f6306a0/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204535043/u/49/f/622900/c/34253/s/1f6306a0/a2t.img" border="0"/>
U.S. asthma rates at all-time high, CDC says
The proportion of Americans with asthma increased from 7.3% in 2001 to 8.4% in 2010, marking the highest level ever, the U.S. Centers for Disease Control and Prevention said Tuesday. In 2010, an estimated 18.7 million adults and 7 million children had the disease -- one in every 12 Americans. Overall, about 29.1 million adults have been diagnosed with asthma at some point in their lives, but many of those were misdiagnosed or have apparently recovered, leading to the current figure of 18.7 million.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f62bd7b/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=U.S.+asthma+rates+at+all-time+high%2C+CDC+says&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-asthma-prevalence-20120515%2C0%2C1500539.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=U.S.+asthma+rates+at+all-time+high%2C+CDC+says&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-asthma-prevalence-20120515%2C0%2C1500539.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204501752/u/49/f/622900/c/34253/s/1f62bd7b/a2.htm"><img src="http://da.feedsportal.com/r/134204501752/u/49/f/622900/c/34253/s/1f62bd7b/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204501752/u/49/f/622900/c/34253/s/1f62bd7b/a2t.img" border="0"/>
Smoking pot for multiple sclerosis? Study finds it helps
Smoking marijuana to relieve the symptoms of multiple sclerosis is a practice with a fair number of adherents, though it has not been subject to rigorous testing. A new study finds that puffing weed does have a rapid and measurable effect on MS patients' muscle spasticity and on their perception of pain. But subjects who smoked pot were not able to walk any faster and -- surprise! -- they felt higher than members of the control group who smoked marijuana stripped of THC.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f5a458b/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Smoking+pot+for+multiple+sclerosis%3F+Study+finds+it+helps&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-marijuana-multiple-sclerosis-20120514%2C0%2C308297.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Smoking+pot+for+multiple+sclerosis%3F+Study+finds+it+helps&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-marijuana-multiple-sclerosis-20120514%2C0%2C308297.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204221522/u/49/f/622900/c/34253/s/1f5a458b/a2.htm"><img src="http://da.feedsportal.com/r/134204221522/u/49/f/622900/c/34253/s/1f5a458b/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204221522/u/49/f/622900/c/34253/s/1f5a458b/a2t.img" border="0"/>
Could patients with COPD breathe easier with acupuncture?
A new study offers some promising evidence that acupuncture may improve quality of life for patients with chronic obstructive pulmonary disease.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f5a458c/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Could+patients+with+COPD+breathe+easier+with+acupuncture%3F&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-acupuncture-copd-breathing-20120514%2C0%2C3314857.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Could+patients+with+COPD+breathe+easier+with+acupuncture%3F&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-acupuncture-copd-breathing-20120514%2C0%2C3314857.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204221521/u/49/f/622900/c/34253/s/1f5a458c/a2.htm"><img src="http://da.feedsportal.com/r/134204221521/u/49/f/622900/c/34253/s/1f5a458c/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204221521/u/49/f/622900/c/34253/s/1f5a458c/a2t.img" border="0"/>
Laxative-free colonoscopy may soon be possible
This post has been corrected. See note at the bottom for details.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f5a0f87/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Laxative-free+colonoscopy+may+soon+be+possible&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-laxative-free-colonoscopy-20120514%2C0%2C6650327.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Laxative-free+colonoscopy+may+soon+be+possible&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-laxative-free-colonoscopy-20120514%2C0%2C6650327.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204456279/u/49/f/622900/c/34253/s/1f5a0f87/a2.htm"><img src="http://da.feedsportal.com/r/134204456279/u/49/f/622900/c/34253/s/1f5a0f87/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204456279/u/49/f/622900/c/34253/s/1f5a0f87/a2t.img" border="0"/>
Sleepwalking: More common than you might think
Ever sleep-walked? I have. At the age of 12, I woke up to find myself in a bedroom where a visiting kid was staying over, my head gently resting on the foot of the bed. I got up, snuck back to my bedroom and kept it to myself. It was weird and a little embarrassing.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f59bd59/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Sleepwalking%3A+More+common+than+you+might+think&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-sleepwalking-is-common-stanford-study-20120514%2C0%2C3214745.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Sleepwalking%3A+More+common+than+you+might+think&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-sleepwalking-is-common-stanford-study-20120514%2C0%2C3214745.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204219046/u/49/f/622900/c/34253/s/1f59bd59/a2.htm"><img src="http://da.feedsportal.com/r/134204219046/u/49/f/622900/c/34253/s/1f59bd59/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204219046/u/49/f/622900/c/34253/s/1f59bd59/a2t.img" border="0"/>
Kids' ER visits resulting from battery exposure have doubled in two decades
Emergency room visits resulting from children swallowing batteries or sticking them into other orifices doubled between 1990 and 2009, researchers said Monday. There were an estimated 5,525 ER visits caused by batteries in 2009, with the bulk of them occurring in children under the age of 5, according to a team from Nationwide Children's Hospital in Columbus, Ohio. Most of them were caused by button batteries, the small, disc-like batteries found in many games and other electronic devices.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f58932f/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Kids%27+ER+visits+resulting+from+battery+exposure+have+doubled+in+two+decades&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-batteries-children-20120514%2C0%2C7382618.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Kids%27+ER+visits+resulting+from+battery+exposure+have+doubled+in+two+decades&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-sci-sn-batteries-children-20120514%2C0%2C7382618.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204447737/u/49/f/622900/c/34253/s/1f58932f/a2.htm"><img src="http://da.feedsportal.com/r/134204447737/u/49/f/622900/c/34253/s/1f58932f/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204447737/u/49/f/622900/c/34253/s/1f58932f/a2t.img" border="0"/>
My kid's pacifier could hurt him. It's worrying -- to a point.
Some of the longest-lasting relics of my kids&rsquo; infancies and toddlerhoods have been their pacifiers and their sippy cups.  Even now, with the boys 3 and 5 years old, we devote two drawers in our kitchen to a collection of jumbled lids, valves and cups (many featuring slowly fading portraits of Lightning McQueen.)  The binkies, which my younger son uses at bedtime and on long airplane trips, live in a banged-up plastic container perched on a high cabinet shelf. <img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f574948/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=My+kid%27s+pacifier+could+hurt+him.++It%27s+worrying+--+to+a+point.&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-bottles-pacifiers-sippy-cups-injuries-20120514%2C0%2C3476896.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=My+kid%27s+pacifier+could+hurt+him.++It%27s+worrying+--+to+a+point.&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-bottles-pacifiers-sippy-cups-injuries-20120514%2C0%2C3476896.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204478968/u/49/f/622900/c/34253/s/1f574948/a2.htm"><img src="http://da.feedsportal.com/r/134204478968/u/49/f/622900/c/34253/s/1f574948/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204478968/u/49/f/622900/c/34253/s/1f574948/a2t.img" border="0"/>
Egg producers fund study confirming the health benefits of eggs
News flash: Eggs are really good for you. This message was brought to you by the American Egg Board.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f49456a/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Egg+producers+fund+study+confirming+the+health+benefits+of+eggs&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-egg-protein-breakfast-diet-20120512%2C0%2C7662035.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Egg+producers+fund+study+confirming+the+health+benefits+of+eggs&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-egg-protein-breakfast-diet-20120512%2C0%2C7662035.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204142559/u/49/f/622900/c/34253/s/1f49456a/kg/326-327/a2.htm"><img src="http://da.feedsportal.com/r/134204142559/u/49/f/622900/c/34253/s/1f49456a/kg/326-327/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204142559/u/49/f/622900/c/34253/s/1f49456a/kg/326-327/a2t.img" border="0"/>
For defibrillators to save lives, people have to use them
Chances are, if you&rsquo;re out and about, you&rsquo;ll pass by an automated external defibrillator, or AED. <img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f46be1f/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=For+defibrillators+to+save+lives%2C+people+have+to+use+them&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-defibrillators-promiximity-blacks-20120511%2C0%2C853207.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=For+defibrillators+to+save+lives%2C+people+have+to+use+them&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-defibrillators-promiximity-blacks-20120511%2C0%2C853207.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204128143/u/49/f/622900/c/34253/s/1f46be1f/a2.htm"><img src="http://da.feedsportal.com/r/134204128143/u/49/f/622900/c/34253/s/1f46be1f/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204128143/u/49/f/622900/c/34253/s/1f46be1f/a2t.img" border="0"/>
Weight-loss drug Lorcaserin: Definite maybe in 2nd run at FDA's OK
The proposed weight-loss drug Lorcaserin, rebuffed in its bid for Food and Drug Administration approval last October, on Thursday won a recommendation of approval from the agency's advisory committee, a major step toward winning the FDA's go-ahead to enter the U.S. market. If the agency follows the advice of the panel of independent experts--which is common but not routine-- Lorcaserin would become the first new prescription weight-loss drug to go on the U.S. market since Orlistat (now marketed over-the-counter as Alli) was approved in 1999.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f3e6660/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Weight-loss+drug+Lorcaserin%3A+Definite+maybe+in+2nd+run+at+FDA%27s+OK&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb--weight-loss-drug-lorcaserin-20120510%2C0%2C2735366.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Weight-loss+drug+Lorcaserin%3A+Definite+maybe+in+2nd+run+at+FDA%27s+OK&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb--weight-loss-drug-lorcaserin-20120510%2C0%2C2735366.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204361805/u/49/f/622900/c/34253/s/1f3e6660/a2.htm"><img src="http://da.feedsportal.com/r/134204361805/u/49/f/622900/c/34253/s/1f3e6660/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204361805/u/49/f/622900/c/34253/s/1f3e6660/a2t.img" border="0"/>
Legalizing gay marriage is good for public health, studies show
President Obama said Wednesday that he now supports gay marriage . In an interview with Robin Roberts of ABC News, he explained that for him, it&rsquo;s an issue of fairness : &ldquo;It's also the Golden Rule, you know, treat others the way you would want to be treated.&rdquo;<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f30d2b0/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Legalizing+gay+marriage+is+good+for+public+health%2C+studies+show&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-gay-marriage-health-studies-20120509%2C0%2C892309.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Legalizing+gay+marriage+is+good+for+public+health%2C+studies+show&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-gay-marriage-health-studies-20120509%2C0%2C892309.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204255229/u/49/f/622900/c/34253/s/1f30d2b0/a2.htm"><img src="http://da.feedsportal.com/r/134204255229/u/49/f/622900/c/34253/s/1f30d2b0/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204255229/u/49/f/622900/c/34253/s/1f30d2b0/a2t.img" border="0"/>
Drug delays progression in myeloma, but is it worth the cost?
Lenalidomide, sold under the tradename Revlimid, significantly improves progression-free survival in patients with myeloma, according to three clinical trials published Wednesday. All three trials were so successful that the results were unblinded early and, in two of the three trials, patients receiving the placebo were switched to the active drug. But researchers also found that the drug doubled the risk of a second, independent cancer occurring, and it is not yet clear whether the drug produces an increase in overall survival. Moreover, the drug is quite expensive, more than $163,000 for a year of treatment, and there was no data indicating whether quality of life improved enough to justify the cost.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f305215/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Drug+delays+progression+in+myeloma%2C+but+is+it+worth+the+cost%3F&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-lenalidomide-myeloma-20120509%2C0%2C2657211.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Drug+delays+progression+in+myeloma%2C+but+is+it+worth+the+cost%3F&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-lenalidomide-myeloma-20120509%2C0%2C2657211.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/134204031879/u/49/f/622900/c/34253/s/1f305215/a2.htm"><img src="http://da.feedsportal.com/r/134204031879/u/49/f/622900/c/34253/s/1f305215/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/134204031879/u/49/f/622900/c/34253/s/1f305215/a2t.img" border="0"/>
1 of 6 cancer deaths worldwide caused by preventable infections
One in every six cancer deaths worldwide is caused by preventable infections, a total of 1.5 million deaths yearly that could be halted by widespread vaccination programs, researchers reported Wednesday. Since 1990, that number has grown by about half a million, suggesting that vaccination programs are losing ground in the battle rather than gaining it.  The vast majority of the cases are caused by three viruses and a bacterium, which are the leading causes of gastric, liver and cervical cancers. Cervical cancers account for about half of the infection-related cancers in women, while liver and gastric cancers account for about 80% of those in men.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f2ebed6/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=1+of+6+cancer+deaths+worldwide+caused+by+preventable+infections&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-infections-cancer-20120509%2C0%2C6630689.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=1+of+6+cancer+deaths+worldwide+caused+by+preventable+infections&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-infections-cancer-20120509%2C0%2C6630689.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/133515424980/u/49/f/622900/c/34253/s/1f2ebed6/a2.htm"><img src="http://da.feedsportal.com/r/133515424980/u/49/f/622900/c/34253/s/1f2ebed6/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/133515424980/u/49/f/622900/c/34253/s/1f2ebed6/a2t.img" border="0"/>
Contaminated reusable grocery bag causes gastric illness outbreak
A reusable grocery bag left in a hotel bathroom caused an outbreak of norovirus-induced diarrhea and nausea that struck nine of 13 members of a girls' soccer team in October, Oregon researchers reported Wednesday. The outbreak also affected many family members after the team returned home.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f2e300a/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=Contaminated+reusable+grocery+bag+causes+gastric+illness+outbreak&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-grocery-bag-diarrhea-20120509%2C0%2C676133.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=Contaminated+reusable+grocery+bag+causes+gastric+illness+outbreak&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-grocery-bag-diarrhea-20120509%2C0%2C676133.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/133515394191/u/49/f/622900/c/34253/s/1f2e300a/a2.htm"><img src="http://da.feedsportal.com/r/133515394191/u/49/f/622900/c/34253/s/1f2e300a/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/133515394191/u/49/f/622900/c/34253/s/1f2e300a/a2t.img" border="0"/>
HBO's 'The Weight of the Nation' is a wake-up call for America
Next week, the combined efforts of an entertainment giant, a health insurance titan, a group of academic heavyweights, a technology philanthropist and two federal agencies bring forth &ldquo;The Weight of the Nation,&rdquo; a four-hour, four-part HBO documentary that gives the nation&rsquo;s obesity crisis a face.<img width='1' height='1' src='http://ChicagoTribune.feedsportal.com/c/34253/f/622900/s/1f2bdf4d/mf.gif' border='0'/><div class='mf-viral'><table border='0'><tr><td valign='middle'><a href="http://share.feedsportal.com/viral/sendEmail.cfm?lang=en&title=HBO%27s+%27The+Weight+of+the+Nation%27+is+a+wake-up+call+for+America&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-hbo-weight-of-the-nation-20120509%2C0%2C3735574.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/emailthis2.gif" border="0" /></a></td><td valign='middle'><a href="http://res.feedsportal.com/viral/bookmark.cfm?title=HBO%27s+%27The+Weight+of+the+Nation%27+is+a+wake-up+call+for+America&link=http%3A%2F%2Fwww.chicagotribune.com%2Fhealth%2Fla-heb-hbo-weight-of-the-nation-20120509%2C0%2C3735574.story%3Ftrack%3Drss" target="_blank"><img src="http://res3.feedsportal.com/images/bookmark.gif" border="0" /></a></td></tr></table></div><br/><br/><a href="http://da.feedsportal.com/r/133515385212/u/49/f/622900/c/34253/s/1f2bdf4d/kg/326-327/a2.htm"><img src="http://da.feedsportal.com/r/133515385212/u/49/f/622900/c/34253/s/1f2bdf4d/kg/326-327/a2.img" border="0"/></a><img width="1" height="1" src="http://pi.feedsportal.com/r/133515385212/u/49/f/622900/c/34253/s/1f2bdf4d/kg/326-327/a2t.img" border="0"/>

 

 


   The AIDS
By Mary Rose
The AIDS-AIDS stands for Acquired Immune Deficiency Read more...

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Development of a measure of the patientprovider relationship in antenatal care and its importance in PMTCT
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Reasons for and correlates of antiretroviral treatment interruptions in a cohort of patients from public and private clinics in southern India
(Source: AIDS Care)
The feasibility of using mobile phone technology for sexual behaviour research in a population vulnerable to HIV: A prospective survey with female sex workers in South India
(Source: AIDS Care)
Messages HIV clinicians use in prevention with positives interventions
(Source: AIDS Care)
Weighing up the burden of care on caregivers of orphan children: The Amajuba District Child Health and Wellbeing Project, South Africa
(Source: AIDS Care)
Rapid psychosocial function screening test identified treatment failure in HIV+ African youth
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Social determinants, lived experiences, and consequences of household food insecurity among persons living with HIV/AIDS on the shore of Lake Victoria, Kenya
(Source: AIDS Care)
The influence of perceptions of HIV infection, care, and identity on care entry
(Source: AIDS Care)
The association of HIV/AIDS treatment side effects with health status, work productivity, and resource use
(Source: AIDS Care)
Economic evaluation of methadone maintenance treatment in HIV/AIDS control among injecting drug users in Dehong, China
(Source: AIDS Care)
Relationship of axis II pathology to sex- and drug-related risk behaviors among patients in HIV primary care
(Source: AIDS Care)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Impact of transitioning from HIV clinical trials to routine medical care on clinical outcomes and patient perceptions
(Source: AIDS Care)
Decision maker priorities for providing antiretroviral therapy in HIV-infected South Africans: A qualitative assessment
(Source: AIDS Care)
Oral versus anal sex at last encounter behavioral differences among men who have sex with men in the District of Columbia
(Source: AIDS Care)
Factor structure and psychometric properties of the European Portuguese version of a questionnaire to assess quality of life in HIV-infected adults: The WHOQOL-HIV-Bref
(Source: AIDS Care)
Uganda: Country Gets $1.6 Billion From Global Fund
[New Vision] The global fight against Aids, Tuberculosis (TB) and malaria has received a major boost of $1.6b in investment funds to projects aimed at saving lives for the period 2012 -14. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Nigeria: Benue, Borno Record 616,396 HIV/Aids Cases, 2,384 TB, 158 Lepers
[Vanguard] Makurdi - Benue and Borno states have expressed alarm over the prevalence of HIV/AIDS in the areas put at 616,396. Benue State Government made this known as the Medical Director of the Federal Medical Centre, Makurdi, Dr. Mathias Oyigeya, asked the Federal Government to establish more hospitals to handle the issue in the state, while Borno State blamed the high incidence of the disease on the past administrations' lack of interest in combating its spread. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: 'When Care Is Missing, It's Suicidal'
[The Herald] Tariro had not taken an HIV test all her life because, apart from the occasional headache and flu, she did not suffer from any life-threatening illnesses. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: 460 Circumcised in Red Cross Week
[Observer] The Uganda Red Cross Society (URCS), on May 8, marked the World Red Cross and Red Crescent Day in memory of the organisation's founder, Henry Dunant. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: Home-Based Saliva HIV Test Kit Coming
[Observer] The Food and Drug Administration (FDA) of the United States yesterday approved the worldwide use of a saliva test kit for HIV detection, just days after a panel recommended the use of Truvada in HIV prevention to the same body. (Source: AllAfrica News: HIV-Aids and STDs)
[News & Analysis] Aids Research: FDA Panel Recommends Anti-HIV Drug for Prevention
On 10 May, the Antiviral Drugs Advisory Committee of the U.S. Food and Drug Administration debated whether an anti-HIV drug should receive approval as a preventive for uninfected people.Author: Jon Cohen (Source: Science: Current Issue)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Predictors of mortality among HIV infected patients taking antiretroviral treatment in Ethiopia: a retrospective cohort study
Conclusion: A lower level of mortality was detected among the cohort of patients on antiretroviraltreatment in eastern Ethiopia. Previous history of weight loss, bedridden functional status atbaseline, low CD4 cell count and advanced WHO status patients had a higher risk of death.Early initiation of ART, provision of nutritional support and strengthening of the food byprescription initiative, and counseling of patients for early presentation to treatment isrecommended. (Source: AIDS Research and Therapy)
Comparison of HIV-positive women with children and without children accessing HIV care and treatment in the IeDEA Central Africa cohort
(Source: AIDS Care)
Join AIDSinfo in Observing HIV Vaccine Awareness Day
May 18, 2012, is the 15th annual observance of HIV Vaccine Awareness Day. This day provides an opportunity to recognize the volunteers, community members, health professionals, and scientists working together toward finding an HIV vaccine. This day is also an opportunity to educate communities across the United States about the importance of HIV vaccine research. Two types of experimental HIV vaccines are currently being studied in clinical trials. Therapeutic HIV vaccines are designed to treat HIV-infected people. Preventive HIV vaccines are designed to prevent HIV infection in people who do not already have HIV. Even though no HIV vaccines are currently available or approved by the Food and Drug Administration (FDA), significant research is under way to develop an effective vaccine. Th...
Join AIDSinfo in Observing National Asian and Pacific Islander HIV/AIDS Awareness Day
May 19, 2012, marks the eighth annual National Asian and Pacific Islander HIV/AIDS Awareness Day. It is a day that serves to increase awareness of the impact of HIV/AIDS among the Asian and Pacific Islander communities in the United States. According to the 2010 HIV Surveillance Report&nbsp;from the Centers for Disease Control and Prevention (CDC), in the 46 states with confidential name-based HIV reporting, Native Hawaiians/Other Pacific Islanders had the third highest rate of new HIV diagnoses among racial and ethnic groups in 2010, following African Americans and Hispanics/Latinos. According to the HIV Surveillance by Race/Ethnicity slide set from CDC, Native Hawaiian/Other Pacific Islander males had a higher rate of HIV diagnoses than that of white males in 2010, and both Asian and Na...
Peer support and improved quality of life among persons living with HIV on antiretroviral treatment: A randomised controlled trial from north-eastern Vietnam
Conclusion: The peer support intervention improved QOL after 12 months among ART patients presenting at clinical stages 3 and 4 at baseline, but it had no impact on QOL among ART patients enrolled at clinical stages 1 and 2. The intervention did not have an effect on Internal AIDS-related stigma. To improve QOL for PLHIV on ART, measures to support adherence should be contextualized in accordance with individual clinical and social needs.KeywordsQuality of life, Peer support, HIV, ART, Quang Ninh, Vietnam, randomised controlled trial (Source: BioMed Central)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
'Virtual Stenting' Aids PCI Planning (CME/CE, with video)
PARIS (MedPage Today) -- Computer projections of the impact of stenting on cardiac ischemia measured by a specialized CT imaging technique appear accurate and could help with planning out placement, researchers found. (Source: MedPage Today Cardiovascular)
Kenya: Funding Hitch Hampers HIV Tribunal Operations
[The Star] The operations of the HIV/Aids Tribunal have been hampered by lack of funds, Parliament was told yesterday. Special Programmes minister Esther Murugi said the funds for the Tribunal were not factored in the budget because it was inaugurated after the 2011/12 financial year. "The Tribunal was inaugurated in July 2011 after the budget allocations had been prepared and approved and thus the tribunal had no funds to carry out its mandate," she said. (Source: AllAfrica News: Health and Medicine)
Uganda: 30,000 At Risk As Taso Closes Treatment Centers
[New Vision] An estimated 30,000 HIV/AIDS patients are at risk following the closure of The AIDS Support Organisation (TASO) outreach centres countrywide. (Source: AllAfrica News: Health and Medicine)
Online STD Partner Notification Becomes Important During OTC HIV Testing Discussion
VALLEJO, Calif., May 17, 2012 (GLOBE NEWSWIRE) -- In order to become the generation which ends AIDS worldwide, society must start progressively moving forward using new tools at its disposal. In an effort to leverage technology and address the prevalence of high-risk sexual behavior, along with a broader age range of sexually active people than ever before, a new website allows people to anonymously notify their former and current sexual partners via email or text that they have been exposed to an STD. (Source: Medical News (via PRIMEZONE))
Simple risk score aids carotid-stenting decisions
The factors determining a patient's risk during carotid surgery are fairly well-understood, but predicting the risk of carotid stenting patients has so far not been easy, so researchers mined the NCDR database to create a simple risk score that predicts in-hospital major adverse cardiovascular events after carotid stenting. (Source: theHeart.org)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Africa: Migrants Living With Aids in South Africa
[Health-e] "Solidarity for Survival" is an exhibition that shows the difficult living conditions that African foreign nationals who have come to seek refuge in South Africa endure. It is currently showing at Constitution Hill, in Johannesburg. Many of the difficulties these migrants face include the lack of access to health care. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: The State of the Media
[RFI] Zuma stands firm on SA's youth wage ... or does he? Are SA trade union's intolerant? Kenya lowers its growth hopes. And how safe are Uganda's anti-retrovirals? (Source: AllAfrica News: HIV-Aids and STDs)
Circle of Life HIV/AIDS-prevention intervention for American Indian and Alaska Native youth.
This article describes the objectives, theoretical bases, development process, and evaluation efforts to-date for the Circle of Life (COL) curricula, HIV/AIDS prevention interventions designed for American Indian and Alaska Native (AI/AN) youth. The curricula are based on Indigenous models of learning and behavior encompassing concepts of Western theories of health behavior change. The curricula underwent extensive national and community review. Subsequent advances include the development of a computer-based version of the intervention. PMID: 22569729 [PubMed - in process] (Source: American Indian and Alaska Native Mental Health Research)
Alaska Native and rural youth views of sexual health: A focus group project on sexually transmitted diseases, HIV/AIDS, and unplanned pregnancy.
Conclusions: One of the fundamental principles of public health practice is community participation, which asserts that success in achieving change is enhanced by the active participation of the intended audience in defining their own high-priority solutions. Our findings-driven by youth themselves-are critical in designing and implementing future sexual health interventions and promoting greater community involvement and acceptance. PMID: 22569722 [PubMed - in process] (Source: American Indian and Alaska Native Mental Health Research)
Does access to a colorectal cancer screening website and/or a nurse-managed telephone help line provided to patients by their family physician increase fecal occult blood test uptake?: A pragmatic cluster randomized controlled trial study protocol
DiscussionThe study intervention has the potential to increase patient fecal occult blood test uptake, decrease colorectal cancer mortality and morbidity, and improve the health of Manitobans. If utilization of the website and/or telephone support line result in clinically significant increases in colorectal cancer screening uptake, changes in screening at the policy- and system-level may be warranted. Trial Registration: clinicaltrials.gov identifier NCT01026753. (Source: BMC Cancer)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model
Conclusions Probiotics can have inflammatory activities in both healthy and IBD tissue. Valid preclinical data on proper model systems should therefore be obtained before specific probiotic strains enter the clinics, especially if administered during acute inflammatory responses. Postbiotics may be a safe alternative for the treatment of patients with IBD in the acute inflammatory phase. (Source: Gut)
von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion
Noncovalent association between the von Willebrand factor (VWF) propeptide (VWFpp) and mature VWF aids N-terminal multimerization and protein compartmentalization in storage granules. This association is currently thought to dissipate after secretion into blood. In the present study, we examined this proposition by quantifying the affinity and kinetics of VWFpp binding to mature VWF using surface plasmon resonance and by developing novel anti-VWF D'D3 mAbs. Our results show that the only binding site for VWFpp in mature VWF is in its D'D3 domain. At pH 6.2 and 10mM Ca2+, conditions mimicking intracellular compartments, VWFpp-VWF binding occurs with high affinity (KD = 0.2nM, koff = 8 x 10&ndash;5 s&ndash;1). Significant, albeit weaker, binding (KD = 25nM, koff = 4 x 10&ndash;3 s&ndash;1) o...
U.S. HIV Aid Has Prevented 741,000 Deaths: StudyU.S. HIV Aid Has Prevented 741,000 Deaths: Study
The United States foreign aid program that sends billions of dollars to African countries for HIV treatment and prevention has cut the number of people dying for any reason in those nations. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Clergy can fight HIV on faith-friendly terms
In the United States, where blacks bear a disproportionate burden of the HIV/AIDS epidemic, black religious institutions could help turn the tide. In a new study based on dozens of interviews and focus groups with 38 of Philadelphia's most influential black religious leaders, physicians and public health researchers find that traditional barriers to preaching about HIV prevention could give way to faith-friendly messages about getting tested and staying on treatment. (Source: ScienceDaily Headlines)
Sudden Cardiac Death in Patients With Human Immunodeficiency Virus Infection
Conclusions: SCDs account for most cardiac and many non-AIDS natural deaths in HIV-infected patients. Further investigation is needed to ascertain underlying mechanisms, which may include inflammation, antiretroviral therapy interruption, and concomitant medications. (Source: Journal of the American College of Cardiology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
FDA Panel Recommends Gilead's Quad for HIVFDA Panel Recommends Gilead's Quad for HIV
A U.S. Food and Drug Administration panel of outside experts has recommended the use of Gilead Sciences Inc's Quad pill for untreated HIV patients. Reuters Health Information (Source: Medscape Hiv-Aids Headlines)
Namibia: Poly Hosts HIV/Aids Awareness Campaign
[New Era] Windhoek - The Polytechnic of Namibia (PoN) last week held its two day 16th HIV/AIDS and Alcohol Awareness Campaign under the theme: No Youth No Future. (Source: AllAfrica News: Health and Medicine)
Sanders: End HIV/AIDS Drug Monopolies
From Congressional Documents & Publications (May 15, 2012) WASHINGTON, May 15 - Sen. Bernie Sanders (I-Vt.) today called for eliminating legal monopolies that make HIV/AIDS medicine so expensive in the United States that many patients cannot... (Source: Drugs.com - Pharma News)
South Africa: Resubmit Proposals for Sex Actually 2012
[Biz-Community] Drama for Life is requesting artists to resubmit proposals for Sex Actually 2012. This is due to technical problems on the website. Drama for Life apologises for the inconvenience and has consequently extended the entry deadline to 21 May 2012. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 'HIV/AIDS On the Increase in Abia'
[Daily Trust] Umuahia - Project Manager of the Abia State Agency for the Control of HIV/AIDS in the state, Dr Sam Ohaeri yesterday said the HIV/AIDS prevalence in the state has increased from three per cent to almost ten per cent. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
U.S. Assistance to Africa Cut AIDS-Related Deaths: Study
Title: U.S. Assistance to Africa Cut AIDS-Related Deaths: StudyCategory: Health NewsCreated: 5/15/2012 6:05:00 PMLast Editorial Review: 5/16/2012 12:00:00 AM (Source: MedicineNet HIV General)
Quality of life aids lung cancer prognosis
Self-reported quality of life at the time of lung cancer diagnosis has a significant impact on patients? survival, show US study results. (Source: MedWire News - Oncology)
Platelet-Activating Factor and Its Basic Metabolic Enzymes in Blood of Naive HIV-Infected Patients
We examined PAF metabolism in blood of naive male patients, 8 with early HIV infection (group A) and 17 just before treatment initiation (group B), versus 18 healthy age-matched males (group C). Statistical analysis was performed with 1-way analysis of variance (ANOVA) criterion and Pearson r test. Higher PAF biosynthesis in patients&rsquo; leukocytes versus group C was accompanied by an increase in lipoprotein-associated phospholipase A2 (Lp-PLA2) activity that degrades PAF. Moreover, PAF synthesis was higher and Lp-PLA2 activity was lower in group B compared to group A. Lipoprotein-associated phospholipase A2 was positively correlated with viral load and negatively correlated with CD4 cell counts in group B. The activities of PAF-basic biosynthetic enzymes in patients&rsquo; leukocytes w...
Disseminated cutaneous histoplasmosis in an immunocompetent adult
We report a rare case of disseminated cutaneous histoplasmosis in an immunocompetent individual. (Source: Indian Journal of Dermatology)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
FDA panel backs OraSure's In-Home HIV test
WASHINGTON (Reuters) - A U.S. Food and Drug Administration panel of outside experts concluded that OraSure Technologies Inc's over-the-counter, in-home HIV test is reasonably safe and effective for determining whether someone has the AIDS virus. (Source: Modern Medicine)
Decision Coaching to Prepare Patients for Making Health Decisions: A Systematic Review of Decision Coaching in Trials of Patient Decision Aids
Conclusions. Compared with usual care, decision coaching improved knowledge. However, the improvement in knowledge was similar when coaching was compared with PtDA alone. Outcomes for other comparisons are more variable, some trials showing positive effects and other trials reporting no difference. Given the small number of trials and variability in results, further research is required to determine the effectiveness of decision coaching. (Source: Medical Decision Making)
People with HIV/AIDS May Be More Prone to Sudden Cardiac Death
In a comprehensive, retrospective 10-year UCSF study, researchers found patients with HIV/AIDS suffered sudden cardiac death at a rate four times higher than the general population. (Source: UCSF Medical Center)
Domestic violence among women living with HIV/AIDS in Kano, Northern Nigeria. - Iliyasu Z, Abubakar IS, Babashani M, Galadanci HS.
Despite the increased risk of domestic violence among women living with HIV/AIDS, its burden has not been adequately explored in many developing countries including Nigeria. Using interviewer administered questionnaires we assessed the prevalence and risk ... (Source: SafetyLit: All (Unduplicated))
What's shame got to do with it: forced sex among married or steady partners in Uganda. - Cash K.
Research objectives were to understand the relationship between sexual, domestic and civil violence and the transmission of HIV/AIDS in Uganda. The focus of this paper is on forced marital sex within the context of Ugandan marital and steady partner relati... (Source: SafetyLit: All (Unduplicated))<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Quality of life aids lung cancer prognosis
Self-reported quality of life at the time of lung cancer diagnosis has a significant impact on patients? survival, show US study results. (Source: MedWire News - Respiratory)
U.S. Assistance to Africa Cut AIDS-Related Deaths: Study
Evaluation attributes more than 740,000 lives saved to the program launched in 2003 (Source: The Doctors Lounge - Health News)
UCLA researchers ID gene variants that speed progression of Parkinson's disease
UCLA researchers may have found a key to determining which Parkinson's disease patients will experience a more rapid decline in motor function, sparking hopes for the development of new therapies and helping identify those who could benefit most from early intervention. &nbsp; In a study published May 15 in the peer-reviewed online journal PLoS ONE, the researchers found that Parkinson's sufferers who possess two specific variants of a gene known to be a risk factor for the disease had a significantly speedier progression toward motor decline than patients without these variants. &nbsp; "This is a relatively small study, with 233 patients, but the effects we're seeing are actually quite large," said Dr. Beate Ritz, vice chair of the department of epidemiology at the UCLA Fielding School of...
740,000 lives saved: Benefits of AIDS relief program
The US President's Emergency Plan for AIDS Relief, the government's far-reaching health-care foreign aid program, has contributed to a significant decline in adult death rates from all causes in Africa, according to a new study. (Source: ScienceDaily Headlines)
Prevalence of obesity and cardiovascular risk in patients with HIV/AIDS in Porto Alegre, Brazil
CONCLUSIONS: Overweight and obesity were highly prevalent. Women were more frequently obese (OR = 3.53; IC 95%, 1.47 < OR < 8.69), and their cardiovascular risk was often higher (OR = 6.97; IC 95%, 4.16 < OR < 11.76). The prevalence of obesity and cardiovascular risk did not change according to antiretroviral therapy or other variables.OBJETIVO: Conhecer a prevalęncia de sobrepeso, obesidade e risco cardiovascular em nossos pacientes ambulatoriais com HIV/AIDS de acordo com o sexo, tratamento antirretroviral e outras variáveis. SUJEITOS E MÉTODOS: Os pacientes foram submetidos ŕ avaliaçăo antropométrica. O índice de massa corporal e a medida da circunferęncia da cintura foram utilizados para classificar o estado nutricional e o risco cardiovascular. RESULTADOS: A maior parte dos 3...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Comparing Cognitive Change After Initial ART RegimensComparing Cognitive Change After Initial ART Regimens
ART initiation improves neurocognitive function in HIV-infected patients. Does one regimen show more improvement than others? HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Kenya: Bunyala Gets Relief Food
[The Star] THE Ministry of Special Programmes through the Bunyala District Disaster Management Committee has distributed relief food to people living with Hiv/Aids and orphaned vulnerable children from Ruambwa sub location in Bunyala East location. (Source: AllAfrica News: HIV-Aids and STDs)
FDA Panel to Consider At-Home HIV Test
Recommendation could usher in a new era of testing (Source: The Doctors Lounge - Health News)
Africa: GBCHealth Conference Introduces MDG Health Alliance
[GBCHealth] NEW YORK CITY (May 15, 2012) - The MDG Health Alliance, an innovative new private sector organization created and led by eminent business leaders to tackle urgent global health problems, was introduced today in the United States at the GBCHealth Conference. (Source: AllAfrica News: HIV-Aids and STDs)
Avoiding the Deer in the Headlight Look at College Graduation
As we come to the college graduation season I so often have seniors who plop themselves down in my office with that deer in the headlight look reporting that they have no idea what to do after graduation. So often they have worked so hard to get through college that they haven?t had the energy or time to really figure out what to do next.read more (Source: Psychology Today Anxiety Center)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Zimbabwe: Nacs ARV Programme Not Free Entitlement for Those Affording
[The Herald] The National Aids Council is worried about the growing gap in funding anti-retroviral drugs for people living with HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: 252,000 Persons to Get HIV Treatment for Five Years
[Daily Trust] A new project run by FHI 360 is to help provide antiretroviral therapy for 252,000 people living with HIV/AIDS over the next five years, including completing ARV treatment for an estimated 41,220 pregnant women across Nigeria. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: It Is Worth Investing in an HIV Positive Child
[Namibian] THERE is delight for any prospective student who reads the word "scholarship" within a box advert in our local newspapers. (Source: AllAfrica News: HIV-Aids and STDs)
South Africa: Antiretroviral Therapy Fights Cervical Cancer in HIV+ Women
[Health-e] Antiretroviral therapy reduces the incidence of pre-cancerous cervical lesions in HIV-positive women, South African investigators reported in the online edition of AIDS. Their study also showed that HIV therapy was associated with a regression of pre-existing lesions. (Source: AllAfrica News: HIV-Aids and STDs)
Upcoming Webinar on Hearing Aids: The Basic Information You Need to Know (5/23/12)
Learn more Wednesday, May 23, 2012 at 2:00 p.m. ET, when FDA&apos;s Center for Devices and Radiological Health (CDRH) will host a 30-minute Webinar to discuss basic information on Hearing Aids. (Source: Food and Drug Adminstration (FDA): CDRHNew)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Use of endogenous NADH fluorescence for real-time in situ visualization of epicardial radiofrequency ablation lesions and gaps
Radiofrequency ablation (RFA) aims to produce lesions that interrupt reentrant circuits or block the spread of electrical activation from sites of abnormal activity. Today, there are limited means for real-time visualization of cardiac muscle tissue injury during RFA procedures. We hypothesized that the fluorescence of endogenous NADH could be used as a marker of cardiac muscle injury during epicardial RFA procedures. Studies were conducted in blood-free and blood-perfused hearts from healthy adult Sprague-Dawley rats and New Zealand rabbits. Radiofrequency was applied to the epicardial surface of the heart using a 4-mm standard blazer ablation catheter. A dual camera optical mapping system was used to monitor NADH fluorescence upon ultraviolet illumination of the epicardial surface and to...
Interventions to improve patient participation in the treatment process for culturally and linguistically diverse people with cancer: A systematic review
AbstractDisparities in cancer outcomes for people from culturally and linguistically diverse (CALD) groups are well known. Improving CALD patients' active participation in treatment processes holds potential to improve outcomes, but little is known of effective strategies to facilitate this. This systematic review investigated interventions to improve three aspects of participation in cancer care among CALD groups, namely involvement in decision?making, communication with health providers and treatment adherence. A comprehensive search of electronic bibliographic databases was conducted to identify intervention studies that reported outcomes relevant to patient participation for CALD groups. Two reviewers independently critically appraised the studies and abstracted data. Of 10?278 pot...
A Causal Framework for Understanding the Effect of Losses to Follow-up on Epidemiologic Analyses in Clinic-based Cohorts: The Case of HIV-infected Patients on Antiretroviral Therapy in Africa
Although clinic-based cohorts are most representative of the "real world," they are susceptible to loss to follow-up. Strategies for managing the impact of loss to follow-up are therefore needed to maximize the value of studies conducted in these cohorts. The authors evaluated adult patients starting antiretroviral therapy at an HIV/AIDS clinic in Uganda, where 29% of patients were lost to follow-up after 2 years (January 1, 2004&ndash;September 30, 2007). Unweighted, inverse probability of censoring weighted (IPCW), and sampling-based approaches (using supplemental data from a sample of lost patients subsequently tracked in the community) were used to identify the predictive value of sex on mortality. Directed acyclic graphs (DAGs) were used to explore the structural basis for bias in eac...
FDA Panel Backs First Rapid, Take Home HIV Test
American consumers may soon be able to test themselves for the virus that causes AIDS in the privacy of their own homes, after a panel of experts on Tuesday recommended approval of the first rapid, over-the-counter HIV test. (Source: RWJF News Digest - Public Health)
Review: Biologic agents increase short-term risk for some adverse events in conditions other than HIV or AIDS.
Authors: PMID: 22586027 [PubMed - in process] (Source: Annals of Internal Medicine)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
People With HIV at Higher Odds of Sudden Cardiac Death
Study finds an increased risk even among patients with well-controlled disease (Source: The Doctors Lounge - Cardiology)
Africa: Board of Global Fund Speeds Up Implementation of Its Strategy
[Global Fund] Geneva - The Board of the Global Fund to Fight AIDS, Tuberculosis and Malaria concluded its 26th Meeting today with broad agreement to direct more than $1.6 billion in available funding into effective programs that save lives, accelerating implementation of the Board's ambitious strategy. (Source: AllAfrica News: HIV-Aids and STDs)
Children don?t have time for the pain?of shots
Feeling &quot;a little&quot; pinch is a small price to pay for good healthcare. But we can do more to reduce the discomfort. (UNICEF Sverige/Flickr) I remember distinctly both of my boys&#8217; 4-month-old well visits. Mostly because of the shots: all four of them. Neither boy was particularly happy about being poked that much (though the shiny Band-Aids afterward did help a little). My wife and I would have loved to help ease the pain of the shots, but we didn&#8217;t have any idea how. Frankly, I don?t know that, in the moment, it crossed our minds that there was something we could do, and it wasn?t something we thought to ask our pediatrician about. I mean, it was just a little bit of pain, right? The problem, though, is that those little bits of pain add up. &#8220;Millions of inj...
Africa: The Global Fund Turns the Tap Back On
[GFO] $1 billion available to fund new grants (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Aidspan's 2011 Annual Report Now Available
[GFO] Aidspan has published its Annual Report for 2011. The report describes how Aidspan performed against its 2011 Annual Plan. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Africa: Secretariat Re-Organisation Was Hindered By Weak Performance Management System, Jaramillo Says
[GFO] "A silo culture had become pervasive" (Source: AllAfrica News: HIV-Aids and STDs)
Africa: Global Fund Launches Process to Select New Executive Director
[GFO] List of 20 "high-impact" countries revealed (Source: AllAfrica News: HIV-Aids and STDs)
NIH statement on HIV Vaccine Awareness Day - May 18, 2012
There is a growing consensus that we can significantly curtail the HIV/AIDS pandemic by implementing scientifically proven HIV prevention strategies, such as voluntary medically supervised adult male circumcision, prevention of mother-to-child transmission and treatment as prevention. (Source: National Institutes of Health (NIH) News Releases)
Zambia: Media Reforms to Help End HIV Stigma
[Times of Zambia] INFORMATION, Broadcasting and Labour Permanent Secretary Amos Malupenga has prodded the media to continue playing a key role in the HIV response by providing the public with sufficient information on the pandemic. (Source: AllAfrica News: HIV-Aids and STDs)
Africa: U.S. Moving Towards a-Pill-a-Day HIV Prevention
[Health-e] HIV prevention groups in the United States have hailed the recommendation by an FDA Advisory Committee that emtricitabine/tenofovir disoproxil fumarate (TDF/FTC or Truvada) be approved for use as pre-exposure prophylaxis (PrEP) among sexually active adult men and women. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Namibia: HIV Scholarship Discrimination Condemned
[New Era] Windhoek - The Legal Assistance Centre (LAC) has condemned countries that make HIV testing a pre-condition for awarding scholarships. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: No Youth, No Future - PoN
[New Era] Windhoek - The Polytechnic of Namibia (PoN) last week launched its 16th annual HIV/AIDS and Alcohol Awareness Campaign, under the theme: No Youth, No Future to highlight the link between HIV and alcohol. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Towards Zero New HIV Infections
[Zimbabwe Standard] "Getting to Zero" stands for the hope that we have for eliminating HIV. We can get to zero new HIV infections, zero discrimination and zero Aids-related deaths, but the challenge is how to get there and how to hold on to the gains made so as not to roll backwards. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Over 350 000 Might Fail to Access ARVs
[The Herald] More than 350 000 people living with HIV and Aids might fail to access anti-retroviral drugs as Zimbabwe could face a US$227 million deficit by 2018, it has been revealed. (Source: AllAfrica News: HIV-Aids and STDs)
Uganda: How a Sex Worker Keeps It Up
[RNW Africa] Prostitutes are good for Uganda's economy. They spend a fortune on clothes, shoes and make-up. They also keep a certain section of the population happy. Yet sex workers are discriminated against and deprived of HIV/AIDS education. Some hope to change that. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Tanzania: Mutual Partnerships in the Health Sector Help Fight and Manage HIV/Aids
[Daily News] By 2007, about 2 million people in Tanzania were estimated to be living with HIV and AIDS with approximately 600,000 (30 per cent) in need of antiretroviral Therapy (ART). (Source: AllAfrica News: HIV-Aids and STDs)
Is the Sexual Behaviour of HIV Patients on Antiretroviral therapy safe or risky in Sub-Saharan Africa? Meta-Analysis and Meta-Regression
Conclusion: In general, this meta-analysis demonstrated a significant reduction in risky sexual behavior among people on ART in sub-Saharan Africa. Future studies should investigate the reproducibility and continuity of the observed positive behavioural changes as the duration of ART lasts a decade or more. (Source: AIDS Research and Therapy)
Are People with HIV/AIDS More Prone to Sudden Cardiac Death?
In a comprehensive, retrospective 10-year UCSF study, researchers found patients with HIV/AIDS suffered sudden cardiac death at a rate four times higher than the general population. (Source: UCSF Medical Center)
T cell independent secondary antibody responses to the envelope protein of simian immunodeficiency virus
Membrane-bound trimeric Env seems to be responsible for the maintenance of high levels of anti-Env antibodies during progression to AIDS. This T cell independent secondary antibody response may prevent T cell-dependent affinity maturation and thus contribute to viral immune escape by favoring persistence of non-protective antibodies. (Source: Retrovirology)
Regulation of ROCK1 via Notch1 during breast cancer cell migration into dense matrices
Conclusion: Increased matrix density elevates ROCK1 activity, which aids in cell migration via cellcontractility. The upregulation of ROCK1 is epigenetically regulated in an indirect mannerinvolving the repression of Notch1. This is demonstrated from inhibition of HDACs by MS-275, which caused an upregulation of Notch1 levels leading to blockade of ROCK1expression. (Source: BMC Cell Biology - Latest articles)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Global tuberculosis control: lessons learnt and future prospects
Authors: Christian Lienhardt, Philippe Glaziou, Mukund Uplekar, Knut Lönnroth, Haileyesus Getahun & Mario Raviglione Tuberculosis (TB) is an ancient disease, but not a disease of the past. After disappearing from the world public health agenda in the 1960s and 1970s, TB returned in the early 1990s for several reasons, including the emergence of the HIV/AIDS pandemic and increases in (Source: Nature Reviews Microbiology)
Bridging knee arthrodesis for limb salvage using an intramedullary cemented nail: a retrospective outcome analysis of a case series
Conclusion&nbsp;&nbsp;Bridging knee arthrodesis with an intramedullary nail is a valuable salvage procedure with acceptable clinical results. As recurring infection remains the most challenging complication, regular clinical and radiological follow-up examinations are necessary following implant-related knee arthrodesis to allow timely intervention in case of loosening. Content Type Journal ArticleCategory Knee Revision SurgeryPages 1-7DOI 10.1007/s00402-012-1534-3Authors Carl Neuerburg, Department of Orthopaedic Surgery, University of Ulm, Oberer Eselsberg 45, 89081 Ulm, GermanyRalf Bieger, Department of Orthopaedic Surgery, University of Ulm, Oberer Eselsberg 45, 89081 Ulm, GermanySebastian Jung, Department of Orthopaedic Surgery, University of Ulm, Oberer Eselsberg 45, 8908...
Zimbabwe: MDC-T Senator Wants Women to Dress Shabbily
[The Herald] WOMEN should always have bald heads, lose weight and dress shabbily to reduce their attractiveness as part of measures to curb the spread of HIV, MDC-T Senator for Chikomo, Morgan Femai said yesterday. Addressing Zimbabwe Parliamentarians on an HIV sensitisation workshop here yesterday, Sen Femai proposed that women should also be circumcised. He said HIV is spreading at an alarming rate because men find it difficult to resist women because they are becoming more attractive. (Source: AllAfrica News: HIV-Aids and STDs)
Treatment of Latent Tuberculosis Infection in HIV: Shorter or Longer?
Abstract&nbsp;&nbsp;Nine months of daily isoniazid is efficacious in treating latent M. tuberculosis infection, but completion rates are low, limiting treatment effectiveness. In 2011, three important studies were published involving novel regimens for the treatment of latent M. tuberculosis infection. At least 36&nbsp;months of isoniazid was more effective than 6&nbsp;months of isoniazid in one study, but not in another?both of which were conducted among tuberculin skin test positive HIV-infected adults living in high tuberculosis incidence settings. Three months of once-weekly isoniazid plus rifapentine or twice-weekly isoniazid plus rifampin (both given under direct observation) resulted in tuberculosis rates similar to those seen with 6&nbsp;months of isoniazid among HIV-infected...
Osteoporosis and Bone Health in HIV
Abstract&nbsp;&nbsp;Patients with HIV can develop several complications that involve bone including low bone mineral density and osteoporosis, osteonecrosis, and rarely osteomalacia. Low bone mineral density leading to osteoporosis is the most common bone pathology. This may result from HIV infection (directly or indirectly), antiretroviral toxicity, or as a consequence of other co-morbidities. The clinical relevance of osteoporosis in HIV infection has been uncertain; however, fragility fractures are increasingly reported in HIV-infected patients. Further research is required to understand the pathogenesis of osteoporosis in HIV-infected patients and determine effective management; however, initiation of antiretroviral therapy seems to accelerate (in the short-term) bone demineraliz...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Highlights from this issue
By the time you read this, Olympic fever will be upon those of us in the UK&mdash;leave is cancelled in the public health agencies, road closure imminent, and a frenzy of emergency planning and resilience exercises is reaching its final stages. Where does sexual health fit in to Olympic preparation? Traditionally, large construction projects and major public events have been seen a magnet for sex work, bringing together large communities of men living apart from partners and families. A before and after analysis exploring Canada's 2010 Winter Olympics suggests that an influx of sex workers is no longer to be expected in a developed setting, but displacement and perceived police harassment need to be addressed.1 Significantly, the researchers noted no increase in new reports of youth or tra...
Why we like clinical guidelines
"What are the best things about BASHH (British Association for Sexual Health and HIV)?" was a question posed in the strategy consultation held in August 2011. Patient care and clinical governance was seen as an &lsquo;extremely high&rsquo; priority for BASHH by almost everyone responding, and the &lsquo;best thing&rsquo; chosen by 96% of the 258 members participating were the clinical guidelines (J Wilson, personal communication). These were given as the main reasons for using the BASHH website by 98% of those responding, and were said to be &lsquo;completely&rsquo; or &lsquo;mostly&rsquo; relevant to their clinical practice. The usage figures for the website substantiate this, with the guidelines receiving nearly 100 000 hits each year,1 a dramatic growth since the first national guidelin...
Knowing your HIV/AIDS epidemic and tailoring an effective response: how did India do it?
Tremendous global efforts have been made to collect data on the HIV/AIDS epidemic. Yet, significant challenges remain for generating and analysing evidence to allocate resources efficiently and implement an effective AIDS response. India offers important lessons and a model for intelligent and integrated use of data on HIV/AIDS for an evidence-based response. Over the past 15&nbsp;years, the number of data sources has expanded and the geographical unit of data generation, analysis and use for planning has shifted from the national to the state, district and now subdistrict level. The authors describe and critically analyse the evolution of data sets in India and how they have been utilised to better understand the epidemic, advance policy, and plan and implement an increasingly effective, ...
Age at first anal sex and HIV/STI vulnerability among gay men in Australia
Conclusions There appears to be a strong link between AFAI and infection with HIV/STIs, as well as tendencies to engage in higher risk sexual behaviour. While further research is needed to understand this link, these findings highlight a need for sexuality education aimed at gay-identified youth to ensure their sexual debut does not lead to poorer sexual health outcomes. (Source: Sexually Transmitted Infections)
Willingness to use HIV pre-exposure prophylaxis and the likelihood of decreased condom use are both associated with unprotected anal intercourse and the perceived likelihood of becoming HIV positive among Australian gay and bisexual men
Conclusions The Australian gay and bisexual men the authors surveyed were cautiously optimistic about PrEP. The minority of men who expressed willingness to use PrEP appear to be appropriate candidates, given that they are likely to report UAIC and to perceive themselves to be at risk of HIV. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Gonorrhoea or chlamydia in a US military HIV-positive cohort
Conclusions Frequent GC and CT diagnoses observed among members of this HIV-positive cohort indicate substantial ongoing risk behaviours that raise concerns for HIV transmission and underscore the need for continued screening to help identify and treat these sexually transmitted infections in this population. (Source: Sexually Transmitted Infections)
The Origins of AIDS
It would be difficult to imagine anyone better qualified than Jacques Pepin to write about the origins of AIDS. An infectious diseases specialist who worked for 4&nbsp;years in a bush hospital in Zaire (now the Democratic Republic of Congo), he trained in epidemiology at the London School of Hygiene & Tropical Medicine, has an encyclopaedic knowledge of French and Belgian colonial history, and has himself conducted groundbreaking research on the epidemiology of HIV-2 in West Africa. This book reads like a detective story, and I found it hard to put down. Starting with the virological evidence that simian immunodeficiency virus in chimpanzees (SIVcpz) was first transmitted to a human around 1920, Pepin takes us through the evidence underlying the &lsquo;cut hunter&rsquo; hypothesis as t...
Injection drug use, sexual risk, violence and STI/HIV among Moscow female sex workers
Conclusions Findings illustrate substantial potential for heterosexual STI/HIV transmission in a setting better known for IDU-related risk. Many of the STI/HIV risks observed are not modifiable by FSWs alone. STI/HIV prevention efforts for this vulnerable population will benefit from reducing coercion and abuse perpetrated by pimps and clients. (Source: Sexually Transmitted Infections)
High prevalence of HIV and sexually transmitted infections among male sex workers in Abidjan, Cote d'Ivoire: need for services tailored to their needs
Conclusions HIV and STI rates found in this study confirm the high risk and vulnerability status of MSW in C&ocirc;te d'Ivoire. There is a definite need for studies exploring risk and risk perceptions among MSW in more depth and for services tailored to their needs, including developing and validating simple algorithms for the diagnosis of STI in MSW and men who have sex with men. (Source: Sexually Transmitted Infections)
HIV and sexually transmitted infections at the borderlands: situational analysis of sexual health in the Brazilian Amazon
Conclusions While the main conditions that contribute to the spread of HIV are in place in the triple-border area, the prevalence of bacterial STIs and HIV are still relatively low, providing a window of opportunity for interventions. (Source: Sexually Transmitted Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Using recent infection testing algorithm tests in clinical practice
Conclusions There are major epidemiological and public health advantages in using RITA testing but there are also advantages to using the RITA test on an individual basis, provided that it is used appropriately. (Source: Sexually Transmitted Infections)
The expansion of HIV-1 in colonial Leopoldville, 1950s: driven by STDs or STD control?
Conclusions It is plausible that the exponential amplification of HIV-1 in L&eacute;opoldville occurred mostly parenterally in the 1950s and sexually in the 1960s. (Source: Sexually Transmitted Infections)
Clinical round-up
Injectable long-acting reversible contraceptive (iLARC) users at higher risk of HIV and Chlamydia trachomatis infections Intuitively, non-barrier forms of contraception increase the risk of sexually transmitted infections. Studies have attempted to quantify the extent of this risk but their results have not been entirely unidirectional. A group of researchers in Durban, South Africa aimed to prospectively analyse the effect of contraception and risk of HIV and Chlamydia in 2236 HIV-negative women1 who were screened for a microbicidal vaginal gel versus placebo HIV prevention trial.2 All women received risk reduction counselling and access to free condoms. Demographic factors were collected at baseline. Self-reported sexual history and contraception use were collected and HIV testing perfor...
Vulnerability of women in common-law marriage to becoming infected with HIV/AIDS: a study of social representations
This article discusses the social representations of women living in common-law marriage in terms of their vulnerability to becoming infected with HIV/AIDS. Data were obtained through the free association of words, and consisted of an excerpt of a study founded on the Social Representations Theory developed with HIV-negative women living in the state capital and cities in the interior of Bahia. The correspondence factor analysis showed significance for the variables: origin, education level and time spent in common-law marriage. Their acceptance of marital affairs emerged as a vulnerability factor for respondents with one to five years spent in common-law marriage, living in cities in the interior. Women from the capital, with 6-10 years spent in common-law marriage, reported monogamy as a...
Gilead's Crucial AIDS Pill Gets Thumbs Up
A panel of advisors to the Food and Drug Administration voted 13 to 1 that the regulator should approve a new once-a-day combo pill for HIV made by Gilead, the leading maker of HIV drugs. The medication is seen as crucial to Gilead's future and poses a threat to Merck's rival pill, Isentress, which must be taken twice a day. (Source: Forbes.com Healthcare News)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
FDA Approves Foscarnet for HIV-Related CMV Retinitis, Herpes FDA Approves Foscarnet for HIV-Related CMV Retinitis, Herpes
The US Food and Drug Administration has approved foscarnet sodium injection in HIV/AIDS-related cytomegalovirus infections and herpes. FDA Approvals (Source: Medscape Hiv-Aids Headlines)
FDA Panel Recommends First Drug for HIV PreventionFDA Panel Recommends First Drug for HIV Prevention
The US Food and Drug Administration's Antiviral Drugs Advisory Committee has recommended approval of Gilead Science's Truvada for preexposure prevention of sexually acquired HIV-1 infection. Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Gilead?s Truvada on course to be first HIV preventative
Gilead Sciences Inc.?s HIV treatment Truvada is a safe and effective as a way to prevent the AIDS virus, an FDA advisory panel said Thursday. Robert McNally, CEO of Atlanta biotech GeoVax Labs Inc. (OTC BB: GOVX), said Truvada?s approval will help control the spread of HIV/AIDS. New incidences of people in the United States contracting HIV has stayed steady for the last 15 to 20 years between 55,000 and 60,000 individuals, said McNally, whose company is developing vaccines to prevent and fight... (Source: bizjournals.com Health Care:Physician Practices headlines)
Kenya: The Cut for Boys to to Tame HIV
[The Star] THE Ministry of Public Health and Sanitation will soon introduce circumcision programme for children under the age of 15 to help curb HIV/Aids in the country. Homa Bay branch DASCOP coordinator Alice Nyambai said they hope to introduce the program to children under 15 years, as a way of supplementing the Voluntary Medical Male Circumcision (VMMC) exercise. (Source: AllAfrica News: Health and Medicine)
Kenya: The Cut for Boys to Tame HIV
[The Star] THE Ministry of Public Health and Sanitation will soon introduce circumcision programme for children under the age of 15 to help curb HIV/Aids in the country. Homa Bay branch DASCOP coordinator Alice Nyambai said they hope to introduce the program to children under 15 years, as a way of supplementing the Voluntary Medical Male Circumcision (VMMC) exercise. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Kenya: Majority in North Eastern Not Aware of HIV Status, Says NACC
[The Star] Only about 10 per cent of the 2.3 million residents of North Eastern know their HIV/Aids status. North Eastern National AIDS Control Council coordinator Julius Koome attributed the low awareness of HIV status among the residents to retrogressive cultural practices. (Source: AllAfrica News: Health and Medicine)
Uganda: Shs257.91 Billion for Treatment of Children Living With HIV
[New Vision] Government has been asked to approve the shs257.91 billion proposed budget for the elimination of HIV/AIDS in children in the financial year Sh2012/2013. (Source: AllAfrica News: Health and Medicine)
Incidence of cancer in children perinatally exposed to nucleoside reverse transcriptase inhibitors: Erratum
No abstract available (Source: AIDS)
South Africa: Demand for Enquiry Into Drug Stockouts
[Health-e] HIV activists and health workers are demanding an enquiry into continuing drug shortages, specifically a number of critical antiretrovirals that are central to government's treatment programme. (Source: AllAfrica News: HIV-Aids and STDs)
Nigeria: Donors Threaten Withdrawal of HIV/Aids Funds to Akwa Ibom
[Daily Trust] Uyo - Chairman, House Committee on Health, Elder Friday Iwok yesterday said that donor agencies are threatening to withdraw their support if the Akwa Ibom State government does not establish an HIV/AIDS control agency. (Source: AllAfrica News: HIV-Aids and STDs)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Africa: Less Global Funds, More Problems
[OSISA] Fund medicines or fund the programmes that support uptake and adherence? That's the choice countries are now facing amid Global Fund shortfalls. With money tight, countries are slashing civil society-led HIV and TB programmes - treatment supporters, community-based volunteers, support for people living with HIV - to safeguard essential services, according to preliminary research being conducted by the Open Society Foundations. (Source: AllAfrica News: HIV-Aids and STDs)
Namibia: Testing Students for HIV for Bursaries - Silly
[New Era] I WILL concur with the Legal Assistance Centre (LAC) in condemning countries that attach going for HIV testing as a pre-condition for awarding scholarships. (Source: AllAfrica News: HIV-Aids and STDs)
Zimbabwe: Raw Deal for HIV+ Renal Patients
[The Herald] Hepatitis B and renal failure remain a threat to people living with HIV. (Source: AllAfrica News: HIV-Aids and STDs)
Flossing or Alternative Interdental Aids?
(Source: Journal of Dental Hygiene)
Pill to prevent HIV gets an FDA endorsement
An advisory panel recommends approval for Truvada, a daily pill that is the first drug shown to protect from the virus that causes AIDS. Critics worry the pill could lead to risky behavior.SILVER SPRING, Md. &#8212; The first drug shown to prevent HIV infection won the endorsement of an FDA advisory panel Thursday, clearing the way for a landmark approval in the 30-year fight against the virus that causes AIDS. (Source: Los Angeles Times - Science)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Africa: Members of Congress Champion Efforts to Prevent and Treat HIV
[E.G. Pediatric Aids Foundation] Washington, D.C. - In advance of Mother's Day, the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) and mothers2mothers (m2m) today welcomed the announcement of a House resolution reaffirming U.S. leadership in efforts to achieve an HIV-free generation. (Source: AllAfrica News: HIV-Aids and STDs)
Female Sex Worker Client Behaviors Lead to Condom Breakage: A Prospective Telephone-Based Survey in Bangalore, South India
We examined condom breakage rates and predictors of breakage in a prospective telephone-based study of female sex workers (FSWs) in Bangalore, India. We obtained data on 3,257 condom-use sex acts, and breakage occurred in 2.1&nbsp;% of these. Situational factors, especially those associated with male clients? behaviors, were the most important predictors of breakage, including sexual inexperience, roughness and violence. Breakage was also associated with having vaginal and anal sex at the same encounter and with poor-fitting condoms. Despite lower than expected breakage rates, the high client volume of FSWs means that there are many unprotected sex acts caused by breakage. Discussions should be held around new education messages, and how programs can respond quickly when sex worker...
Tanzania: Gender Based Violence Campaign Launched in Serengeti
[Daily News] ON May 5, hundreds of people from all walks of life gathered at Maburi village in Serengeti district of Mara Region to witness the official launch of a fresh programme aimed at cutting down gender based violence and the spread of HIV/AIDS in the area. (Source: AllAfrica News: HIV-Aids and STDs)
Botswana-Baylor pediatric HIV clinic Teen Club program amping up social support
Ten years ago, HIV-positive children in Botswana were not expected to reach, much less survive, adolescence. With the opening of the Botswana-Baylor Children's Clinical Centre of Excellence in 2003 and new funding from private and public sources, these children were given access to life-saving therapies and their life expectancy dramatically changed &ndash; for the better. Today, there is an abundance of HIV-positive adolescents in Botswana who must learn how to manage their chronic illness and transition into adulthood. The Botswana-Baylor Children's Clinical Centre of Excellence Teen Club was established shortly after the Botswana children's center opened to help them do just that. &quot;We started basically out of a computer lab in the children's center,&quot; said Ed Pettitt, senior pr...
FDA Advisers Back Pill to Help Prevent HIV Infection
Truvada intended for at-risk individuals, including gay and bisexual men and heterosexual couples with one HIV-infected person (Source: The Doctors Lounge - Infections)<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
Can self-reported height and weight be used among people living with HIV/AIDS?
To assess the reliability and validity of self-reported height and weight in adults living with HIV/AIDS (ALWHA) we assessed 508 ALWHA of both genders on antiretroviral therapy. Height and weight were directly measured in a subsample. Sensitivity and specificity analysis were performed to determine the validity of self-reported measures. Bland&ndash;Altman's method was used to calculate the limits of agreement between values while reliability was assessed using intraclass coefficients. Regression equations were devised to determine actual measures from self-reported values. Mean differences among measured and self-reported weight were &ndash;0.96 kg for men and &ndash;0.54 kg for women. Mean height differences were less than 2 cm, yielding good reliability for body mass index (BMI). Overwe...
Migration/mobility and risk factors for HIV among female sex workers in Andhra Pradesh, India: implications for HIV prevention
We examined the relation between high mobility/migration (sex work in three or more villages/towns within the past year) and HIV risk factors among a sample of female sex workers (FSWs) in Andhra Pradesh, India. We recruited FSWs aged &ge;18 years (n = 673) through respondent-driven sampling for a survey on HIV risk. Adjusted logistic and linear regression models assessed high mobility in relation to sexual and physical victimization, sexually transmitted infection (STI) symptoms and treatment, condom use and negotiation, number and/or types of sex trades, number of clients and number of days worked. Twelve percent (n = 82) of FSWs were highly mobile; those with high mobility were more likely to report recent HIV risk factors: sexual violence (adjusted odds ratio [AOR] = 5.2; 95% confidenc...
Condom use among female sex workers and their non-commercial partners: effects of a sexual risk intervention in two Mexican cities
The purpose of this study was to examine whether a brief behavioural intervention promoting condom use among female sex workers (FSWs) and their clients had the added benefit of increasing condom use among FSWs and their steady, non-commercial partners (e.g. husbands, boyfriends). Participants were 362 FSWs, aged &ge;18 years, living in Tijuana or Ciudad Juarez, Mexico, who received a behavioural intervention to promote condom use with clients. Repeated-measures negative binomial regression was used to assess FSWs&rsquo; condom use with steady partners versus clients across time. Results showed that FSWs engaged in unprotected sex with steady partners more than with their clients, and that the intervention changed FSWs&rsquo; condom use with clients but not their steady partners. HIV-preve...
Use of conjoint analysis to assess HIV vaccine acceptability: feasibility of an innovation in the assessment of consumer health-care preferences
We examined the feasibility of using conjoint analysis to assess future HIV vaccine acceptability among three diverse communities: a multiethnic sample in Los Angeles, CA, USA (n = 143); a Thai resident sample in Los Angeles (three groups; n = 27) and an Aboriginal peoples sample in Toronto (n = 13). Efficacy had the greatest impact on acceptability for all three groups, followed by cross-clade protection, side-effects and duration of protection in the Los Angeles sample; side-effects and duration of protection in the Thai-Los Angeles sample; and number of doses and duration of protection in the Aboriginal peoples-Toronto sample. Conjoint analysis provided insights into universal and population-specific preferences among diverse end users of future HIV vaccines, with implications for evide...
Human papillomavirus prevalence, cervical abnormalities and risk factors among female sex workers in Lima, Peru
Female sex workers (FSWs) are at high risk of human papillomavirus (HPV) infection. Questionnaires were administered to 200 FSWs aged 18&ndash;26 years in Lima, Peru, to gather risk behaviours, and cervical swab samples were collected for Pap smears and HPV DNA testing as part of a longitudinal study. Participants reported a median of 120 clients in the past month, and 99.2% reported using condoms with clients. The prevalence of any HPV in cervical samples was 66.8%; 34 (17.1%) participants had prevalent HPV 16 or 18, and 92 (46.2%) had one or more oncogenic types. Fifteen women had abnormal Pap smears, 13 of which were HPV DNA positive. Fewer years since first sex was associated with oncogenic HPV prevalence in a model adjusted for previous sexually transmitted infection (STI) status and ...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
A systematic review and meta-analysis of the prevalence of chlamydia, gonorrhoea and syphilis in incarcerated persons
Communicable diseases are common in people who are incarcerated. We aimed to define the prevalence of chlamydia, gonorrhoea and syphilis in people who are incarcerated and to identify subgroups with the highest risk of infection. We searched for prevalence studies of chlamydia, gonorrhoea or syphilis in incarcerated populations. Pooled estimates were generated, and meta-regression was conducted. Random effects models yielded pooled prevalence estimates of 5.75% (95% confidence interval [CI] 5.01, 6.48) and 12.31% (95% CI 10.61, 14.01) for chlamydia in men and women, 1.4% (95% CI 1.09, 1.70) and 5.73% (4.76, 6.69) for gonorrhoea in men and women, and 2.45% (95% CI 2.08, 2.82) and 6.10% (95% CI 4.75, 7.46) for syphilis in men and women, respectively. Each infection was associated with female...
Pruritus in HIV-infected patients in the era of combination antiretroviral therapy: a study of its prevalence and causes
Pruritus is a common symptom in HIV-infected patients. However, there is a lack of studies examining this symptom. We investigated the prevalence of pruritus and its causes in this population by offering the possibility of participating in a skin health programme to all HIV-infected patients who attended our service in Alicante, Spain. Those who accepted (n = 303) underwent an interview and a detailed physical examination by specialists from the Dermatology Department. Between May 2003 and October 2003, 94 patients (31%) reported pruritus: xerosis, seborrhoeic eczema and interdigital tinea pedis were the most frequent dermatological entities responsible for this symptom. Patients with pruritus had higher viral loads (P = 0.006). We conclude that pruritus is still a frequent symptom in HIV-...
Adeno-associated virus may play a protective role against human papillomavirus-induced cervical lesions independent of HIV serostatus
This study investigated the prevalence of adeno-associated virus (AAV) and human papillomavirus (HPV) DNA in cervical samples of HIV-seropositive and -seronegative women attending a clinic in south-eastern Brazil. Both viruses were investigated by polymerase chain reaction (PCR) and cytological exams were performed. AAV was typed by PCR and restriction fragment length polymorphism analysis. AAV prevalence was 19.7% (56/284), with 18.7% (21/112) and 20.3% (35/172) in HIV-positive and -negative women, respectively. AAV type 2 was the single virus type detected. AAV was detected with higher frequency in HPV-infected women (P &lt; 0.05) as was HPV in HIV-positive women (P &lt; 0.05). The AAV&ndash;HPV co-infected women showed a lower rate of atypical squamous cells of undetermined significance...
The relationship between HIV testing and CD4 counts at HIV diagnosis among newly diagnosed HIV-1 patients in Japan
The aim of this study was to investigate the factors relating to CD4 level at HIV diagnosis and HIV testing behaviour. Participants were newly diagnosed patients (n = 654) in Japan from 2000 to 2005. Around 75% of participants were diagnosed at hospital and clinics. Mean CD4 counts at diagnosis through voluntary HIV testing, screening tests and testing due to concomitant sexually transmitted infection (STI) were 368, 336 and 316 cells/&mu;L, respectively. In contrast, the mean CD4 count where testing was due to the presence of HIV-related clinical symptoms was 151 cells/&mu;L (P &lt; 0.0001). Compared with those diagnosed at their first HIV test, those who had undertaken multiple HIV tests prior to diagnosis showed CD4 counts that increased significantly (P &lt; 0.0001) in relation to the ...
Sexual risk behaviours, condom use and sexually transmitted infection treatment-seeking behaviours among female sex workers and truck drivers in Uganda
We assessed sexual risk behaviours, condom use and sexually transmitted infection (STI) treatment-seeking behaviours among truckers and female sex workers (FSWs) operating at 12 hotspots along two major transport corridors in Uganda. Participants were identified through local contact persons: 261 truckers and 259 FSWs were interviewed. FSWs reported a mean number of 28 partners in the past 30 days while truckers reported a mean of seven partners. Ninety-four percent of FSWs and 87% of truckers reported condom use in the past month; however, only 21% of truckers and 45% of FSWs reported using condoms consistently during that time. More than half of truckers (n = 261) and 77% of FSWs (n = 259) reported that they suffered from STIs in the past year, and 93% of FSWs and 92.9% of truckers sough...<div id="medworm"><p><b><i>MedWorm Sponsor Message:</i></b> Have a look at <a href="http://www.theinfectiousdiseasesdaily.com/">The Infectious Diseases Daily</a>, the new MedWorm portal for infectious disease specialists, updated daily with all the latest infectious diseases news and research.</p></div>
HIV prevalence among men who have sex with men in New Zealand 1985-2009: 25 years of public health monitoring
Annual population-based estimates of the number of men who have sex with men (MSM) with diagnosed HIV infection (HIV prevalence pool), and the proportion of all MSM this represents (HIV prevalence), have been insufficiently described over the long term. We investigated the dynamic effects of ongoing HIV diagnoses, lower mortality due to treatment and growth in the MSM population over time on these two epidemic indicators using national HIV/AIDS surveillance data in New Zealand, 1985&ndash;2009. The diagnosed HIV prevalence pool rose 79% between 1989 and 1999, and 137% between 1999 and 2009. Estimates of diagnosed HIV prevalence as a proportion of MSM were 0.2% of MSM in 1985, and were between 1.5% and 5.0% of MSM by 2009. New Zealand continues to have a relatively low-prevalence HIV epidem...
Survey of lactation suppression in HIV-positive pregnant women
The risk of HIV transmission via breastfeeding is well reported. We conducted a national survey in the UK to look at the current knowledge and postpartum practice of HIV physicians caring for HIV-positive pregnant women. In total, 167 questionnaires were distributed, 85 (51%) questionnaires were returned. All the respondents advised their patients against breastfeeding, 17 (23%) respondents routinely prescribed drugs for postpartum lactation suppression and 32 (43%) detailed awareness of interactions between antiretroviral therapy and dopaminergic lactation suppression agents. Thirteen respondents reported awareness of guidance on lactation suppression. The knowledge and use of lactation suppression agents appears to be low. However, its use will not only reduce postnatal mastitis and brea...
A survey of the sexual and reproductive health of HIV-positive women in Leicester
This project reports results from a questionnaire survey of sexual practices, contraception use and pregnancy plans in HIV-positive women in Leicester, UK, in order to establish the need for a dedicated sexual and reproductive health (SRH) clinic. The majority (96%) of women were aware of the benefits of antiretroviral therapy (ART) in pregnancy and 39% were planning a future pregnancy. Most (74%) used condoms consistently but their use decreased with the addition of another contraceptive method. Condoms were mostly obtained from non-National Health Service (NHS) settings. Long-acting reversible contraception (LARC) use was higher in this group of women than the general population and mainly provided by family planning services. A dedicated SRH clinic was thought to be useful by 79% of wom...
HIV-associated neurocognitive disorder: rate of referral for neurorehabilitation and psychiatric co-morbidity
Despite advances in antiretroviral therapy, HIV-infected patients continue to present with HIV-associated neurocognitive disorder (HAND) which may be associated with significant psychiatric co-morbidity. We audited our patients with HAND referred for psychiatric assessment against the National Service Framework guidelines that they should receive neurorehabilitation. We found that despite these patients posing a risk to themselves and others due to poor insight and medication adherence, high rates of psychiatric co-morbidity and severely challenging behaviour, few were referred for neurorehabilitation. We recommend that clear referral pathways for psychiatric intervention and neurorehabilitation are established in HIV treatment centres. (Source: International Journal of STD and AIDS)

 

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